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2006-09-25

Weak Immunity May Drive Tough-To-Treat Sinusitis

Weak Immunity May Drive Tough-to-Treat Sinusitis

Some more of Granny's Health Remedies and Wisdom
Please note:
THIS PUBLISHER IS NOT PRESCRIBING MEDICINE,
TREATMENTS OR REMEDIES BUT SIMPLY PASSING
ON TO YOU INFORMATION DESCRIBING FORMULAS, ETC. THAT OTHER PEOPLE HAVE FOUND USEFUL.

Weak Immunity May Drive Tough-to-Treat Sinusitis

For small group of patients, drugs and surgery don't work

Weakened immune responses inside the nose may help explain chronic sinusitis that does not respond to treatment, according to new research.

Chronic sinusitis is persistent inflammation of the moist tissue that lines the nose and sinus cavities, resulting in clogged passages and recurrent infections.

This condition is usually treated with antibiotics, decongestants and steroids, but when medications fail, surgery can help keep the passages open. Unfortunately, nearly one in 10 of people treated with medications or surgery see symptoms return within weeks or months.

In a new study, a Johns Hopkins University team compared cells of the mucous membrane lining the nose from nine patients who benefited from surgery with nine who did not. They will present the findings Tuesday at the annual scientific sessions of the American Academy of Otolaryngology, Head and Neck Surgery.

The team found that, in people who did not benefit from surgery, the activity of at least four genes in the body's nasal immune defense system were severely decreased, and their production of two proteins critical to this defense was 20 to 200 times below normal.

"The nose's first line of defense is the epithelium [lining], and when the local innate immune function is curtailed, infections can get a head start, which might serve to worsen the sinus inflammation," Andrew Lane, associate professor at Johns Hopkins University School of Medicine and director of its rhinology and sinus surgery center, explained in a prepared statement.

More information

The American Academy of Family Physicians has more about sinusitiis.

SOURCE: Johns Hopkins Medical Institutions, news release, Sept. 15, 2006

Toni Shrader

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2006-09-20

Strokes May Follow "Body Clock"

Strokes May Follow 'Body Clock'

Strokes May Follow 'Body Clock'
They usually strike in morning or early evening, study finds

Strokes may be timed to the body's internal clock, Japanese researchers say.

Researchers at Iwate Medical University analyzed data from 13,000 patients who had one of three types of stroke -- cerebral infarction, subarachnoid hemorrhage, intracerebral hemorrhage -- for the first time.

All three kinds of strokes had two periods of peak occurrence: one between 6 a.m. and 8 a.m. and another between 6 p.m. and 8 p.m. Stroke occurrence declined significantly during sleep.

Upon closer analysis, the researchers did find that cerebral infarction -- where blood flow to the brain is restricted -- had a higher peak in the morning and a lower peak in the afternoon than the other two kinds of stroke, which were more likely to have lower peaks in the morning and higher peaks in the afternoon.

About 20 percent of cerebral infarction occurred during sleep, with most of them concentrated in the time immediately before waking up, although it's likely the stroke would have actually begun earlier, the study authors said.

The findings were published in the Aug. 17 online edition of the Journal of Neurology, Neurosurgery and Psychiatry.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about stroke.
-- Robert Preidt

SOURCE: BMJ Specialist Journals, news release, Aug. 17, 2006

Toni Shrader

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2006-09-17

Orange Juice Best At Stopping Kidney Stones

Orange Juice Best at Stopping Kidney Stones

Orange Juice Best at Stopping Kidney Stones
It outperformed lemonade and other citrus juices, study found

An independent study finds that orange juice beats lemonade and other citrus fruit juices in helping to keep kidney stones at bay.

Experts have long known that potassium citrate -- found in citrus juice -- can slow kidney stone formation in people with a history of the condition.

But this study, by a team from the University of Texas Southwestern Medical Center at Dallas, found that other components can affect a juice's ability to prevent stones.

Thirteen volunteers (some with a history of kidney stones and some without) took part in the multi-phase trial, which was funded by the U.S. National Institutes of Health. For one week, participants drank distilled water, for another week orange juice, and then lemonade for another week. There was a three-week interval between each of these weeks.

During each phase, the participants drank 13 ounces of orange juice, lemonade or distilled water three times a day with meals. They were also put on a low-calcium, low-oxalate diet, which also helps cut stone formation.

The study found that orange juice increased levels of citrate in the urine and reduced the crystallization of uric acid and calcium oxalate, the most common components of kidney stones. Lemonade did not increase citrate levels.

"One reason might be the different constituents of various beverages," study lead author Dr. Clarita Odvina, assistant professor of internal medicine at the Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, said in a prepared statement.

Odvina noted that the citrate in orange and grapefruit is accompanied by a potassium ion while the citrate in lemonade and cranberry juice is accompanied by a hydrogen ion. While hydrogen ions counteract the beneficial effects of high citrate content, potassium ions do not.

The study is available online and was expected to be published in the Oct. 26 print issue of the Clinical Journal of the American Society of Nephrology.

More information

The American Medical Association has more about kidney stones.

SOURCE: University of Texas Southwestern Medical Center, news release, Aug. 31, 2006

Toni Shrader

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Posted at 01:43:10 PM | Post Comment | Read Comments (0)

2006-09-03

Know Your Blood Pressure

Some more of Granny's Health Remedies and Wisdom

Please note:
THIS PUBLISHER IS NOT PRESCRIBING MEDICINE,
TREATMENTS OR REMEDIES BUT SIMPLY PASSING
ON TO YOU INFORMATION DESCRIBING FORMULAS, ETC. THAT OTHER PEOPLE HAVE FOUND USEFUL.

Know Your Blood Pressure
Are your pressure and cholesterol levels within normal range?

Blood pressure and cholesterol levels are excellent indicators of heart disease risk. If your levels are in or nearing the dangerous range, you'll need to take action to protect your heart and your health.

But what are those levels? Here's a list of recommendations, courtesy of the American Heart Association:

Normal blood pressure, taken at rest, should be 120/80 millimeters of mercury (mm Hg) or lower. High blood pressure is considered 140/90 mm Hg or higher, and prehypertension is any reading between normal and high blood pressure.

People with blood pressure in the prehypertensive range (between 120 and 139 systolic pressure and 80 and 90 diastolic pressure) should make lifestyle changes to prevent heart disease.

Total cholesterol should be below 200 mg/dL. High cholesterol is any reading of 240 mg/dL or higher, and moderate risk is anything in between normal and high cholesterol.

LDL is "bad" cholesterol. That reading should be below 100 mg/dL, and anything higher than 160 mg/dL is considered a high risk for heart disease.

HDL is "good" cholesterol. That reading should be between 40-50 mg/dL for men and 50-60 mg/dL for women. Anything less than 40 mg/dL is considered a high risk for heart disease.

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Posted at 02:03:59 PM | Post Comment | Read Comments (0)

2006-09-01

Low Testosterone

Low Testosterone Could Increase Death Risk

Some more of Granny's Health Remedies and Wisdom

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Low Testosterone Could Increase Death Risk
Association was seen in men over 40, although reasons aren't clear

Low testosterone may boost death risk in men over 40, a new study finds.

A U.S. team found that older males with relatively low testosterone had an 88 percent increased risk of death compared with their counterparts with normal testosterone levels, researchers report.

"This is really an unusual finding. The exact mechanism of this needs to be worked out," said lead researcher Dr. Molly M. Shores of the Veterans Administration Puget Sound Health Care System and University of Washington, Seattle.

The report was published in the Aug. 14/28 issue of the Archives of Internal Medicine.

As men age, their testosterone levels gradually decline. After 30 years of age, levels decrease by about 1.5 percent per year. Low testosterone levels can result in decreased muscle mass and bone density, insulin resistance and low sex drive, as well as less energy, more irritability and feelings of depression, the researchers noted.

In the study, Shores and her colleagues looked at the whether low testosterone levels were associated with an increased risk of death in 858 men over 40.

Among older men, 19 percent had low testosterone levels, 28 percent had an equivocal testosterone level, meaning that their tests revealed an equal number of low and normal levels, and 53 percent had normal levels.

"Low testosterone in older men was associated with an increased risk for mortality," Shores concluded. During 4.3 years of follow-up, 20.1 percent of men with normal testosterone levels died, compared with 24.6 percent of the men with equivocal levels and 34.9 percent of the men with low testosterone levels, Shores's team found.

testosterone levels can be affected by illness, surgery and other medical problems. But even when the researchers excluded men who had died within the first year of follow-up, those with low testosterone levels were still 68 percent more likely to die compare to men with normal levels of the hormone, Shores noted.

It's not yet clear whether low testosterone helps cause illness and death, Shores said. Men who have chronic illnesses typically have low testosterone levels, she noted. So, "it may be that men who are ill have a low testosterone level and then they have a higher death rate," she said.

Shores suggests that men who think they might have low circulating testosterone discuss it with their doctor. testosterone supplementation is an option, but Shores cautioned against it, saying the risk and benefits of such treatment aren't yet known.

One expert said the findings aren't overly surprising.

"This confirms similar data from the Massachusetts Male Aging Study," said Dr. Andre T. Guay, the director of the Center for Sexual Function/Endocrinology at the Lahey Clinic in Peabody, Mass. "Shores's diagnosis of low testosterone is lower than others use, so people with really low testosterone levels are at risk," he added.

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Toni Shrader

Toni Shrader is the owner of Senior Highway a website devoted to resources for the elderly and convalescent caregivers. Senior Highway

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Posted at 05:44:40 PM | Post Comment | Read Comments (0)

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